中兽医药及疾病防控方向
陈武（1966年～），男，教授，博士。1999年6月中国农业大学与日本麻布大学联合培养临床兽医学中西兽医结合方向博士研究生毕业。北京市人才强教深化计划学术创新团队带头人，动物科学技术学院科技与研究生工作副院长。
主讲《中兽医学》、《中西结合兽医临床技术》”、《中兽医针灸及方剂学》等本科和研究生课程，负责“中国传统兽医学国际培训研究中心”留学进修人员的的培训工作。
主持国家及省部级科研项目多项，在研的项目有“电针对犬痿证的理气活血效应研究”（国家基金2009-2011年）， “小动物临床疑难病中西结合研究”（中日合作项目2006-2011年）及北京市人才强教深化计划“动物抗炎－促生长中药研究” 学术创新团队项目（2011-2013年）。
目前中药抗炎和环核苷酸磷酸二酯酶相关的研究工作取得一定进展。在小动物临床运动机能障碍、心血管病和皮肤病等疑难病的中西结合诊疗方面受到国内外同行专家和社会的好评。现兼任中国传统兽医学国际培训研究中心负责人、亚洲兽医传统医学会常务理事秘书长，中国畜牧兽医学会兽医影像技术分会副理事长、中国畜牧兽医学会中兽医分会常务理事、农业部新兽药审评专家、中国兽药典委员会委员，北京小动物诊疗行业协会副理事长，日本麻布大学客座教授（2008年4月-），日本公益财团法人动物临床医学研究所特聘教授/客座研究员。
穆 祥
Mu xiang
(1960-)
穆祥，江苏启东人，1960年2月出生，北京农学院二级教授、临床兽医学和基础兽医学硕士生导师、兽医学(中医药)北京市重点实验室副主任，北京市中药方剂防治动物传染性疾病机理及其有效成分研究学术创新团队带头人，兼任中国农业大学、西北农林科技大学、南京农业大学、吉林大学博士生合作指导教师。现为亚洲传统兽医学会副理事长、北京解剖学会副理事长、中国畜牧兽医学会常务理事、中国解剖学会理事、中国畜牧兽医学会中兽医学分会副理事长、中国畜牧兽医学会动物解剖学和组织胚胎学分会常务理事、中国兽医协会中兽医学分会副理事长、北京畜牧兽医学会秘书长、中国针灸学会经络研究会委员、中华人民共和国农业部第一届动物防疫专家委员会委员、农业部第五届新兽药审评委员。
1984年7月毕业于北京农业大学兽医系中兽医专业，获农学学士，1987年7月毕业于西北农业大学兽医系动物神经解剖专业，获农学硕士，1987年至今，任教于北京农学院。1995-2005年任北京农学院动物科学技术系系主任。2001年入选教育部高层次优秀创新人才，2005年入选北京市教委优秀创新团队带头人。
工作以来，曾主讲过动物解剖学、动物组织胚胎学、中兽医学、畜产品原料学、动物医学专业教育概论等课程，现主讲动物解剖学、动物组织胚胎学、动物细胞环境学。曾主编教材2部、副主编教材1部、参编教材2部，副主持完成市教委教改项目1个。曾负责北京农学院临床兽医学学科建设，形成了以中兽医学、胚胎工程为特色方向的市级重点学科。
工作以来，相继主持、副主持北京市自然科学基金、国家自然科学基金、农业部“九.五”攻关项目、教育部、973课题、北京市教委创新团队项目等资助的项目25个。共发表论文196篇、副主编著作3部。科研主攻方向：中(兽)医药防治疾病的现代机制与动物维持细胞环境结构即微血管间的相关性研究，已形成较完整的、独特的理论体系。提出并证实穴位的实质是皮内具有特异性舒缩频率和同步舒缩功能的微循环单元；提出并证实经脉的实质是有序态的微血管网络；提出并基本证实，针灸治疗疾病的作用机理在于提高穴区微血管网络自律运动的振幅后，经直接传递和神经节段性反射途径使脏器内具有相同自律运动频率的微血管群产生共振，进而实现阻断致病因子的作用和实质细胞微环境的改善；提出中药方剂防治疾病的机理在于调控微血管功能进而改善细胞微环境的观点；提出并证实抗细菌毒素致微血管内皮细胞伤害是中药方剂防治细菌性疾病的主要机制；在国际上首次成功培养了大鼠的肠黏膜微血管内皮细胞，创建利用体外培养的微血管内皮细胞来筛选中药有效成分的技术平台；提出了“微血管系统是动物体维持细胞环境的结构”、“中(兽)医药学是通过保护、激活微血管达到防治疾病目的的一门学科”的观点。
刘爵，男，1966年生，博士（后），现为北京市农林科学院畜牧兽医研究所研究员。2000年中国农业大学博士研究生毕业。2000年至2002年新加坡国立大学分子农业生物学院访问科学家（Visiting Scientist）。2002年至2006年新加坡国立大学淡马锡生命科学研究院（前身为分子农业生物学院）博士后研究员（Research Fellow）。中国畜牧兽医学会禽病学分会理事、世界禽病学会会员、北京微生物学会兽医微生物委员会委员。国家肉鸡产业技术体系疾病控制研究室岗位专家。2008年入选北京市市级新世纪百千万人才工程。
研究方向为动物分子病毒学与传染病防制。主要从事重要畜禽疾病的分子致病机制与免疫预防及诊断技术研究。
主持或参加国家科技部科技攻关项目、国家攀登计划项目、863项目，北京市科技合同项目、科技新星项目、自然科学基金项目，及新加坡科学技术管理局资助项目等多项研究。现主持的项目有：国家现代肉鸡产业技术体系疾病控制功能研究室分子病毒学岗位专家（2009-2013）经费：350万元；国家自然科学基金项目，“细胞分裂原活化蛋白激酶信号通路参与猪2型圆环病毒感染的分子机制”（2009.01-2011.12）经费：30万元；北京市科委农业科技成果转化专项，“猪鸡主要疫病诊断试剂盒研究与开发”（2009.04-2011.12）经费：100万元。
以第一完成人获2006年农业部“新兽药注册证书”和2007年度北京市科学技术三等奖， 参与建立并完成《传染性囊病诊断技术》国家标准（第二完成人）。在国际权威病毒学刊物如《JournalofVirology》、《Virology》和《VirusGenes》上第一作者或通讯作者发表SCI收录论文14篇。
张涛
（1980-），男，副教授，2008年中国农业大学基础兽医学专业博士毕业，主要从事中兽医药防治动物疾病的相关研究，在中药作用机理与其调控微血管内皮细胞功能的相关性、经穴区微血管的生理特性等方面的研究取得了一定进展，持国家自然科学基金（编号31001083）、北京市教委科技计划项目（编号KM201110020014）等课题4项，参加“973”计划项目、国家自然科学基金、北京市自然科学基金等课题6项，发表论文30余篇，其中SCI收录期刊4篇，获北京市科学技术三等奖1项，获国家发明专利2项，通过教育部科技发展中心成果鉴定1项，参编北京市高等教育精品教材1部。
电话：010-80793027，E-amil：zhangtao8008@126.com
姜代勋（1978年～），男，副研究员，博士。2007年6月中国农业大学临床兽医学中兽医方向博士研究生毕业。2007年7月至今在北京农学院兽医学（中医药）北京市重点实验室工作。主持并参与国家及省部级科研项目多项，现主持的项目有“磷酸二酯酶4中药抑制剂对肺微血管内皮细胞黏附分子表达的作用研究”（国家自然科学基金2012-2014年），“磷酸二酯酶4在中性粒细胞黏附中的作用及相关中药调控研究”（北京市自然科学基金2011-2013年）、“白芍和芦根抑制磷酸二酯酶4抗炎成分的筛选及应用”（北京市教委项目2010-2012年）。目前主要从事中药抗炎机理及针灸相关作用机理研究，在磷酸二酯酶的表达、活性检测与中药调控研究及针灸治疗动物“痿证”机理等方面取得了一定进展。在国内外学术期刊发表论文10余篇。现兼任亚洲传统兽医学会副秘书长。
Dr. Daixun Jiang (1978～), male, associate professor. He graduated from the China Agricultural University and obtained PhD degree of clinical veterinary medicine in June, 2007, then worked at Beijing Key Laboratory of Traditional Chinese Veterinary Medicine up to now. He presides and participates in several national and provincial scientific research projects, and now preside the projects such as “Study of phosphodiesterase 4 herbal inhibitor on cellular adhesion molecule expression in pulmonary microvascular endothelial cells” (National Natural Science Foundation, 2012-2014), “Study on the effect of phosphodiesterase 4 in neutrophil adhesion and the relative herbal regulation” (Beijing Natural Science Foundation, 2011-2013) and ” Anti-inflammatory ingredients’ screening and application in phosphodiesterase 4 inhibitive herbs Baishao and Lugen” (General Program of Science and Technology Planning Program of Beijing Municipal Commission of Education, 2010-2012). At present, he mainly goes in for the researches about the anti-inflammatory mechanism of herbs and related acupuncture mechanism of action, and has made certain progress in the study of phosphodiesterase expression, activity assay and the regulation of herbs and the mechanism of acupuncture treating animal “flaccidity syndrome”. He has published more than 10 research papers in the domestic and foreign academic journals. Now he serves as the vice secretary-general of Asian Society of Traditional Veterinary Medicine.
董 虹：农学博士，副教授，硕士生导师
电话：010-80799480
E-mail：donghong523@163.com
通讯地址：北京市昌平区回龙观北农路7号 兽医学（中医药）北京市重点实验室 邮编：102206
董虹（1978-），女，农学博士，北京农学院动物科学技术学院副教授。2008年获中国农业大学临床兽医学中兽医专业博士学位，主要从事中兽药防治动物疾病分子机制方面的研究。目前主持国家自然科学基金青年（31101850）1项，题目为“提高微血管自律运动振幅的中药成分抗致病因子伤害的机制研究” ；主持北京市自然科学基金项目（6132007）1项，题目为“细菌毒素损伤微血管内皮细胞后对嗜中性粒细胞活性的影响及抗菌中药的调控机制” ；主持北京市教委科技面上项目（KM201210020008）1项，题目为“犀角地黄汤退热机制的研究”；主持北京农学院三项基金重点项目（2177516001）1项，题目为“清热解毒类中药退热作用机制探讨及其有效成分筛选”；主持北京市科协面上项目1项，题目为“平胃散提取物制备及临床药效研究”。参与国家十一五科技支撑计划、十二五科技支撑计划、973等多个项目；是北京市教委人才强教深化计划-创新团队的成员之一。发表文章20余篇，参与编著书籍2部，获国家发明专利3项，通过教育部科技发展中心成果鉴定1项。目前兼任北京畜牧兽医学会理事和华北区中兽医学会理事。
Hong Dong: PhD. Associate Professor.
Beijing Key Laboratory of Traditional Chinese Veterinary Medicine,
Animal Science and Technology College, Beijing University of Agriculture.
Tel：+86-10-80799480
E-mail：donghong523@163.com
Address：NO. 7 Beinong Road, Huilongguan Town, Changping District, Beijing 102206, China.
Dr. Hong Dong (1978- ), graduated with a B.S. from The Rongchang campus of Southwestern University in 2001, and then obtained Ph.D. from China Agricultural University of Traditional Veterinary medicine. Dr. Dong is now an associate professor in the Beijing Key Laboratory of TCVM, Beijing University of Agriculture, with her research interests specially focusing on molecular mechanism research of Traditional Veterinary Medicine on prevention and control of animal diseases.
Grant Support:
National Natural Science Foundation of China “The Mechanism of Chinese Medicine Ingredients Increasing the Amplitude of Vasomotion of Microvascular Endothelial Cell Resist Damage of Pathogenic Factor” (31101850 PI) 2012.1-2014.12
Beijing Natural Science Foundation“The effect of microvascular endothelial cell damaged by bacteriotoxin on neutrophil activity and the regulation mechanisms of Chinese medical prescription” (6132007 PI) 2013.1-2015.15
Science and Technology Project of Beijing Municipal Education Commission “The Antipyretic Mechanism of XijiaoDihuang Decoction” (KM201210020008 PI) 2012.1-2014.12
The State Key Program of three funds of Beijing University of Agriculture “The Antipyretic Mechanism of Chinese Medicine and Screening of Effective Components” (PI) 2011.1-2012.12
Beijing Association for Science and Technology Project “Extract Preparation of PingWei Powder and Clinical Pharmacodynamic research” (PI) 2011.1-2012.12
Representative Publications
1. Hong Dong., Zhang Y.D., Liu F.H., Yang K., Yu J., Xu J.Q.. Regulating Effects and Mechanisms of Chinese Medicine Decoction on Growth and Gut Hormone Expression in Heat Stressed Pigs. Livestock Science, 2012, 143:77-84
2. Hong Dong, Xiaoyu Liu, Tao Zhang, Daixun Jiang, Effects of astragaloside increased the amplitude of microvascular vasomotion on the gene expression of rat myocardium microvascular endotheliasl cells. 4th Conference of the Asian Society of Traditional Veterinary Medicine, 2012, 71-72
3. Hong Dong., Wu W., Ma Z., Lv J., Zhang T., Mu X. Acute Toxicity and Pharmacodynamics Experiment of Mubingxiaohuang Powder. Chinese Journal of Veterinary Medicine, 2011,47(1):52-54
4. Hong Dong, Liu F.H., Yang K., Xu J.Q.. Traditional Chinese medicine prescription enhances intestinal digestion and absorption in heat stress rats by regulating the CCK, SST GAST and GIP. The Journal of Japanese Society of Traditional Veterinary Medicine, 2010, 18(1):171-182
5. Hong Dong, Yang K., Mu X., Liu F.H., Xu J.Q.. Effects of Chinese medicinal prescription on Jejunum Hsp70 in rat under heat stimulation. Chinese Journal of Veterinary Medicine. 2010, 12: 10-12.
6. Hong Dong, Liu F.H., Mu X., Zhang Y.D., Xu J.Q. Effect of Sijunzi Decoction on the Expression of mRNA of VIP and SS of Beijing Duck with Spleen Deficiency. Acta Veterinaria et Zootechnica Sinica, 2006, 37(10): 042-1046
7. Hong Dong, Mu X., Liu F.H., Wang Z.L., Xu J.Q. Effect of Dangshen and Baizhu on Expression of mRNA of CCK, VIP and SS from Beijing Duck with Spleen Deficiency. Chinese Journal of Animal Science, 2006, 42(23):22-25
8. Hong Dong, Mu X., Liu F.H., Zhang Y.D., Xu J.Q. Cloning and sequencing analysis of VIP gene from Beijing duck. Journal of China Agricultural University. 2006, 11(4): 29-32
9. Hong Dong, Liu F.H., Zhang Y.D., Xu J.Q. Advance in the Effects of Functional Regulation of Exocrine Pancreatic Secretion. Progress in Veterinary Medicine, 2005, 26(10): 19-22
兽医产科及胚胎方向
郭勇，1963年生，教授，硕士生导师, 2006年度北京市中青年骨干教师，中国畜牧兽医学会动物繁殖分会常务理事。1985年毕业于北京农学院畜牧专业，获农学学士学位；1996年于中国农业科学院研究生院获农学硕士学位（方向：动物生物技术）；2001年毕业于中国农业大学生物学院，获理学博士学位（方向：动物生理与生殖内分泌）。2003年1月至2005年5月，在美国Vanderbilt大学医学中心儿科系生殖生物学与发育生物学分部Dr. Dey的实验室从事博士后研究，研究方向为：小鼠早期胚胎着床的分子机理。
主要从事动物遗传学、分子生物学、动物生殖内分泌和动物生物技术的教学工作，侧重畜禽生殖机理（尤其是家畜早期胚胎着床机理、蛋用种公鸡营养与生殖机能相关性、以及提高种用畜禽综合繁殖力等方面）的研究。曾作为骨干人员参加完成了部分国家“863十五课题”、“中国－俄罗斯转基因动物（动物生物反应器）合作研究项目”以及国家杰出青年基金项目各1项，主持科技部攻关项目子课题1项，并入选“2006年度北京市中青年骨干教师”。现主持国家“十二五转基因生物新品种培育科技重大专项”一级子课题2项、2013年度国家自然基金面上项目1项、同时从2012年起担任“北京市产业创新体系家禽创新团队”营养与功能岗位专家；此外，已完成（主持）2009年度国家自然基金面上项目1项，以及2006年度国家人事部和2007年度教育部“留学人员科技活动择优资助启动类项目”各1项；合作主持2009年度北京市自然基金重点项目1项，并主要参加国家“十一五转基因生物新品种培育科技重大专项”、“十n五国家科技支撑计划”、“十一五国家863计划”、“十二五国家863计划”重点项目二级子课题7项、2010年度国家自然基金面上项目1项、2011年度国家自然基金面上项目1项，以及北京市教委科技重点项目1项。发表论文70余篇，其中在Nature Medicine、PNAS、JCI、JBC和BOR等国际著名SCI期刊发表文章11篇，第一作者文章单篇影响因子最高为5.85（JBC），总计影响因子约为86.0。
CURRICULUM VITAE
NAME: Guo，Yong
GENDER: Male
DATE OF BIRTH: May 28, 1963
PLACE OF BIRTH: Shanghai , China
CITIZENSHIP: China
ADDRESS:
Office:
Department of Animal Science and Technology
Beijing University of Agriculture
Changping District, Huilongguan Beinong Road 7
Beijing , 102206
China
TELEPHONES:
Office: ( 8610) - 80799133
Fax: (8610) - 80799468
E-MAIL: y63guo@yahoo.com.cn
EDUCATION
|
Institution and Location
|
Degree
|
Year
Conferred
|
Filed of Study
|
|
Beijing Agricultural College
Institute of Animal Science, Chinese Academy of Agricultural Sciences
China Agricultural University
|
B.S.
M.S.
Ph.D.
|
1985
1996
2001
|
Animal Science
Reproductive Physiology and Animal Biotechnology
Animal Reproductive
Biology, Cell Biology and Endocrinology
|
ENGLISH PROFICIENCY
In 1987, receiving the Certificate for Proficiency in English from the Graduate School of Foreign Language Center of China Scientific and Technical University. In 1999, receiving the Certificate of PET-5 ( The highest grade of Public English Test in China).
ACADEMIC APPOINTMENT
1985-1992: Lecturer in the Department of Animal Husbandry and Veterinary Science of Beijing Agricultural College.
1992-1997: Assistant Professor in the Department of Animal Husbandry and Veterinary Science of Beijing Agricultural College.
1998-2002: Associated Professor in the Department of Animal Science and Technology of Beijing Agricultural College.
2003.1-2005.5: Postdoctoral Research Fellow in the Division of Reproductive & Developmental Biology, Department of Pediatrics, Vanderbilt University Medical Center. U. S. A
2005.5-2007.9: Associated Professor in the Department of Animal Science and Technology of Beijing University of Agriculture.
2007.12-2009.12: Professor in the Department of Animal Science and Technology of Beijing University of Agriculture.
2009.12- Professor in the College of Animal Science and Technology of Beijing University of Agriculture.
PROFESSIONAL AND RESEARCH EXPERIENCE
1985-1992: Focusing on teaching Poultry Science and Cattle Science in the Department of Animal Sciences in Beijing Agricultural College, and doing some research work on genetics and breeding of light layers, and on the application of some reproductive techniques (such as embryo transfer, embryo freezing, et al.) for dairy cattles.
1993-1997: Focusing on the nuclear transfer of bovine embryos, and production of transgenic rabbits and goats. Five transgenic rabbits (Human Insulin like Growth Factor-1, hIGF-1) and two transgenic goats (Bovine β-casein) were identified transgenic positively by Southern Blot Hybridization. Microinjection of foreign genes (such as bovine chamosin and hIGF-1) into bovine IVF (in vitro fertilization) embryos was also conducted. Construction of recombinant plasmids for gene transfer and positive transgenic animals were detected by PCR and Southern Blot Hybridization.
1998-2002: Focusing on the mechanism of murine oocyte maturation by researching on the effects of recombinant human follicle stimulating hormone, recombinant human luteinizing hormone and recombinant human chorionic gonadotropin on the development of murine pre-implantation embryos.
2003.1-2005.5: As a postdoctoral research fellow in the Division of Reproductive and Developmental Biology in the Department of Pediatrics of Vanderbilt University Medical Center, Nashville, TN (mentor: S.K. Dey). Focusing on the special field of preimplantation and implantation biology as following:
1). Roles of lipid mediators in ovulation, fertilization and implantation using mutant mice.
2). Ligand-receptor signaling with endocannabinoids in early embryo development and implantation
HONOURS
1997 “Jingjiu - He Houhua Teacher Award ” from Beijing Agricultural College
2006 As a fellow of the Funding Project for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality( PHB or IHLB )in 2006( from 2006 to 2008 ).
Grant Support
National Fund for Natural Sciences of China ( 31272526, PI ) 2013/01/01 – 2016/12/31
The goal of this project is to explore the mechanism of the regulation of IFNτ,ISG15 and Wnt7a on different pre-implantation bovine embryos. [ $13,500,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant ( 2013ZX08008-005-03, PI ) 2013/01/01—2013/12/31
The goal of this project is to breed a new transgenic anti-arthritis encephalitis ovine breed. [ $8,340,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant ( 2011ZX08008-005-03, PI ) 2011/08/01—2012/12/31
The goal of this project is to breed a new transgenic anti-arthritis encephalitis ovine breed. [ $8,340,0]
National Fund for Natural Sciences of China ( 30871836, PI ) 2009/01/01 – 2011/12/31
The goal of this project is to explore the mechanism of the regulation of both IFNτand Galectin15 on early implantation of ovine IVF embryos.[ $4,500,0]
Municipal Key Fund for Natural Sciences of Beijing Municipal Government
The goal of this project is to explore the functional analysis of both mouse and bovine trophoderm stem cells. [ $2,990,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant ( 2008ZX08008-005-02, Co-investigator, PI: Liu Yun-hai )
The goal of this project is to breed a new transgenic anti-arthritis encephalitis ovine breed. [ $19,400,0]
2008/08/01 – 2010/12/31
National Eleventh “5-year-plan” “863 High Tech Major Plan” of China---Sub-grant ( 2008AA1003，Co-investigator, PI: Ni Hemin )
The goal of this project is to explore the mechanism of in vitro maturation for ovine oocytes . [ $4,500,0]
2009/01/01 – 2011/12/31
PUBLICATIONS
1. Zhang Shaoyu, Liu Yunhai, Ni Hemin, Wang Hao, Gu Meichao, Yan Peng, Yang Fei, Guo Yong*, Gene expression profile analysis of dormant mouse embryos preserved by controlled slow freezing, Acta Laboratorium Animals Scientia Sinica ,2012, 20(5): 15-19, (*: correspondence author)
2. Chen Li-ping, Piao Xue-jiao, Luo Yong, Ni He-min, Liu Yun-hai, Guo Yong*, Study on the in-vitro cultured methods for the uterine endometrical cells of dairy cattles and sheep, Chinese Agricultural Science Bulletin, 2012, 28(14): 99-104,(*: correspondence author)
3. Li Kai#, Ni He-min#, Liu Yun-hai, Zhao Yan-wei, Qu Yang-yan, Li Xiao-yan, Guo Yong*, LH plays a role to enhance the nuclear and cytoplasm synchronization for in vitro maturation of ovine oocytes, Scientia Agricultura Sinica,2011, 10（1）：136-141；(#：co-first author, *: correspondence author, indexed by SCIE)
4. Ni He-min, Zhang Hong-bo, Liu Yun-hai, Deng Gui-xin, Lu Tian-gang, Guo Yong*, The distribution of LH receptor on the ovaries among three different sheep breeds by different efficiency of superovulation, Acta Veterinaria et Zootechnica Sinica, 2011, 42(11): 1625-1631,
5. Ni He-min, Zhang Hong-bo, Liu Yun-hai, Lu Tian-gang, Deng Gui-xin, Guo Yong*, Distribution of FSH receptor on the ovaries among different sheep breeds by different efficiency of superovulation, Scientia Agricultura Sinica,2011, 44（6）：1232-1238；
6. Tian Yu-jing, Lu Wen-geng, Zhang Yu, Lin Hao, Ni He-min, Guo Yong*, Isolation and cultivation of bovine trophoblastic stem-like cell lines, Chinese Agricultural Science Bulletin, 2011, 27(26): 20-24,
7. Lin ZL, Gao Y, Deng GX, Liang HB, Zhang HB, Liu YH, Ni HM, Guo Y, Wang ZHG, Effect of estrus synchronization with PMSG and FSH on the distribution of estrogen receptor α in the mouse uterus, ovary and fallopian tube, Acta Laboratorium Animals Scientia Sinica ,2010, 18(3): 204-207,
8. Gao Y, Lin ZL, Zhang HB, Liang HB, Liu YH, Guo Y, Ni HM, Comparison of the expression of estrogen receptor α in mouse endometrium between those treated by estrus synchronization and in natural estrus, Acta Laboratorium Animals Scientia Sinica ,2010, 18(2): 168-171,
9. Liang HB, Liu JQ, Li FH, Xu HT, Niu JY, Li J, Sun Y, Guo Y, Liu YH, Comparison of different methods for boar sperm capacitation by CTC staining, China Animal Husbandry and Veterinary Medicine, 2010, 37(4): 171-173,
10. Liu YJ, Xia Y, Jin JN, Guo R, Liu YH, Guo Y, Li JH, Wei XL, Effect od different durations treated by luteinizing hormone on maturation in vitro of bovine oocytes, China Animal Husbandry and Veterinary Medicine, 2010, 37(5): 123-125,
11. Liu LQ, Guo Y, Liu YH, Xue JZH, Zhang H, Li XY, Ni HM, Effect of Calcium Ionophore and Caffeine on Ovine Sperm Capacitation in vitro, China Animal Husbandry and Veterinary Medicine, 2010, 37(1): 112-115,
12. Li K#, Ni HM#, Liu YH, Zhao YW, Qu YY, Li XY, Guo Y*, LH plays a role to enhance the nuclear and cytoplasm synchronization for in vitro maturation of ovine oocytes, Scientia Agricultura Sinica,2009(10): 42(10):3633-3638, (*: correspondence author)
13. Li K, Mu YL, Han JL, Yang SL, Liu L, Yuan XX, Guo Y, Feng ST, Study on genetic variation of inbred families of Wuzhishan miniature pig using microsatellite DNA loci. Acta Veterinaria et Zootechnica Sinica, 2009, 40(3): 296-302,
14. Qin GS, Li HJ, Liang HB, Guo Y, Ni HM, Liu YH, In vitro production of early dairy cattle embryos by using X-bearing sperm. Chinese Journal of Animal Science, 2009,
15. Liu LQ, Liu YH, Guo Y, Yang FG, Ni HM, Comparison of the ovine sperm capacitation and fertilization in vitro among different concentration of serum collected from their different estrous stages. Acta Veterinaria et Zootechnica Sinica, 2009, 40(8): 1150-1156,
16. Qu YY, Liu YH, Guo Y, Li K, Zhao YW, Li XY, Ni HM, The tendency of mitochondrial distribution during maturation in vitro of ovine oocytes. Acta Veterinaria et Zootechnica Sinica, 2009, 40(8): 1258-1261,
17. Liu JW, Ni HM, Guo Y, Xu Y, Bao WY, Liu YH, Murine parthenogenetic embryonic development can be improved by the associated chemical activation. Chinese Journal of Zoology, 2009, 44(4): 135-141,
18. Li K, Feng ST, Mu YL, Yang SL,Han JL, Liu L, Yuan XX, Guo Y, Study on genetic regulation of microsatellite loci gene of three inbred families of Wuzhishan miniature pig. Scientia Agricultura Sinica, 2009, 42(5): 1751-1760,
19. Wu J, Ni HM, Liu YH, Guo Y, Bao WY, Xu Y, Wang XZ. Effect of different durations on nuclear maturation in vitro of feline oocytes. China Animal Husbandry and Veterinary Medicine, 2009, 36(3): 102-105,
20. Zhang HB, Qin GS, Liu YH, Guo Y, Li XY, Liu LQ, Ni HM. Effect of estrogen and progesterone on the distribution of progesterone receptor on mouse endometrium of different pubescent ways. Acta Laboratorium Animals Scientia Sinica ,2009, 17(3): 206-209,
21. Bao WY, Liu YH, Guo Y, Xu Y, Wu J, Ni HM. Determination of the ovulation duration for domestic cats after superovulation during their non-breeding seasons. China Animal Husbandry and Veterinary Medicine, 2009, 35(10): 72-74
22. Liu LQ, Zhou WB, Gu S, Yang FG, Guo Y*. Ovine Sperm Capacitation is not Affected by Their Reproductive Ducts during Different Reproductive Phases.Chinese Journal of Animal Science, 2008, 44(3): 13-15,
23. Zhang H, Liu YH, Ni HM, Yang FG, Liu LQ, Guo Y*. Effect of Different Co-culture Cell Types on the Development of Ovine Parthenogenetic Embryos. Heilongjiang Animal Science and Veterinary Medicine, 2008, 316(5): 8-12,
24. Li XY, Ni HM, Liu YH, Zhao YW, Qu YY, Liu JW, Guo Y*. Effect of PGE2 ,PGF2α and
Iloprost on Development in vitro of 2-cell Mouse Embryos. Acta Laboratorium Animals Scientia Sinica , 2008, 16(2): 122-126,
25. Bao WY, Liu YH, Guo Y, Xu Y, Wu J, Ni HM. Determination of the ovulation duration for domestic cats after superovulation during their Non-breeding seasons. China Animal Husbandry and Veterinary Medicine,2008, 35(10): 72-74,
26. Li K, Zhao YW, Guo Y, Liu YH, Lu TG, Qu YY, Ni HM, Effect of E2 and P4 on maturation in vitro of oocytes from Kunming mouse. Acta Laboratorium Animals Scientia Sinica , 2008, 16(4): 293-297,
27. Yang FG, Ni HM, Guo Y, Liu LQ, Zhang H, Liu YH. Effect of Butyrolactone on in vitro maturation and fertilization of Ovine Oocytes. Journal of Agricultural Biotechnology, 2008, 16(1): 66-70,
28. Liu LQ, Liu YH, Ni HM, Xue JZ, Zhang JT, Bai JL, Guo Y*. Comparision of Ovine Sperm Capacitation in Different Animal Reproductive Ducts. Heilongjiang Animal Science and Veterinary Medicine, 2008, 312(1): 27-29,
29. Yang FG, Guo Y, Ni HM, Zhang H, Liu LQ, Xue JZ,Liu YH. Effect of Medium and Duration on In Vitro Maturation and Development of Ovine Parthenogenetic Embryos. Heilongjiang Animal Science and Veterinary Medicine, 2008, 312(1): 33-35,
30. ZHAO YW, LI K, Qu YY, LU TG, Liu YH, Guo Y, Ni HM. Effect of LH and hCG on
In Vitro Maturation of Oocytes from Kunming Mouse. Chinese Journal of Comparative Medicine, 2008, 18(2): 23-27,
31. Tranguch S, Chakrabarty A, Guo Y, Wang H, Dey SK. Maternal Pentraxin 3 Deficiency Compromises Implantation in Mice. Biol Reprod, 2007, 77(3): 425-432,
32. Yang FG, Liu YH, Ni HM, Zhang H, Guo Y*. Effect of Butyrolactone on Maturation in vitro and Developmental Competence of Ovine Oocytes. Chinese Journal of Animal Science, 2007, 43(23): 7-10,
33. Liu LQ, Liu CS, Guo Y, Ni HM, Zhang H, Yang FG, Liu YH. Comparison of CTC Staining and in Vitro Fertilization among Different Ovine Sperm Capacitation Methods. China Animal Husbandry and Veterinary Medicine, 2007,34(8): 31-34,
34. Zhang H, Liu YH, Ni HM, Yang FG, Liu LQ, Xue JZ, Guo Y*. Effect of Media and Serum Concentration on Development of Ovine Parthenogenetic Embryos. China Animal Husbandry and Veterinary Medicine, 2007,34(7): 32-34,
35. Xue JZ, Liu YH, Guo Y, Liu LQ, Zhang H, Yang FG, Ni HM. Effect of Different Concentrations of Progesterone on Ovine Sperm Capacitation in vitro, Journal of Guangxi Agric and Biol Science, 2006, 25(supp): 63-66,
36. Wang D, Wang H, Guo Y, Ning W, Katkuri S, Wahli W, Desvergne B, Dey SK, Dubois RN. Crosstalk between peroxisome proliferator-activated receptor {delta} and VEGF stimulates cancer progression. Proc Natl Acad Sci U S A. 2006 103（50）：19069-74，
37. Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF, Dey SK. Fatty acid amide hydrolase deficiency limits early pregnancy events. J Clin Invest. 2006, 116(8): 2122-2131，
38. Yong Guo#, Haibin Wang#, Yasuo Okamoto, Natsuo Ueda, Philip J. Kingsley, Lawrence J. Marnett, Harald H. O. Schmid, Sanjoy K. Das, and Sudhansu K. Dey. N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation. The Journal of Biological Chemistry, 2005, 280(25): 23429-23432, (#equal contribution)
39. S. Tranguch, T. Daikoku, Y. Guo, H. Wang and S.K. Dey. Molecular complexity in establishing uterine receptivity and implantation. Cellular and Molecular Life Sciences, 2005, 62: 1964-73,
40. Haibin Wang, Yong Guo, Dingzhi Wang, Philip J Kingsley, Lawrence J Marnett, Sanjoy K Das, Raymond N Dubois & Sudhansu K Dey. Aberrant cannabinoid signaling impairs oviductal transport of embryos. Nature Medicine , 2004, 10 (10): 1074-80,
41. Daikoku T, Song H, Guo Y, Riesewijk A, Mosselman S, Das SK, Dey SK. Uterine Msx-1 and Wnt4 signaling becomes aberrant in mice with the loss of leukemia inhibitory factor or Hoxa-10: Evidence for a novel cytokine-homeobox-Wnt signaling in implantation. Mol Endocrinol. 2004, 18(5): 1238-50,
42. Wang H, Matsumoto H, Guo Y, Paria BC, Roberts RL, and Dey SK. Differential G-protein coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. Proc Natl Acad Sci USA , 2003, 100(25): 14914-14919,
43. Wang S, Xia G, Bu S, Xie H, Wang J, Guo Y. Effect of sodium nitroprusside (a donor of nitric oxide) on the spontaneous maturation of mouse oocyte in vitro. Acta Laboratorium Animals Scientia Sinica. 2003, 11 (2): 88-91,
44. Shumin Bu, Guoliang Xia, Huirong Xie, Yong Guo. Nitric oxide produced by cumulus cells stimulates maturation of mouse oocytes. Chinese Science Bulletin. 2003, 48(1): 72-75,
45. Guo Yong, Xia GL, Wang H, Xie H, Lei L, and Bu S. Effects of recombinant human LH on the early embryo development in mice. Acta Zoologica Sinica . 2002, 48 (6): 754-758;
46. Shumin Bu, Guoliang Xia, Huirong Xie, Yong Guo. Nitric oxide produced by cumulus cells stimulates maturation of mouse oocytes. Chinese Science Bulletin. 2002, 47: 1730-1733,
47. Wang H, Xia GL, Taya K, Xie H, and Guo Y . Ontogeny of cytochrome P450 side chain cleavage enzyme in the mouse ovary. Journal of Agricultural Biotechnology. 2002, 10 (1): 36-39,
48. Guo Yong, Xia Guoliang, Lei Lei, Bo Shumin, Xie Huirong. Effect of recombinant human luteinizing hormone on the development of murine oocytes fertilization in vitro, Acta Laboratorium Animals Scientia Sinica , 2001, (4): 227-229,
49. Lei lei, Guo Yong, Yang W, Xie H, Wang H, and Xia GL. Mechanisms of induced ovulation by recombinant human gonadotropins in mice. Progress in Natural Science. 2001, 12(8): 857-860,
50. Wang H, Xia GL, Li M, Guo Yong, and Xie H . Effects of epidermal growth factor on the follicle development and estradiol secretion of mouse fetal ovary induced by follicle-stimulating hormone in vitro. Journal of Agricultural Biotechnology. 2001, 9 (1): 37-40,
51. Wang H, Li M, Xia GL, Lu Z, Guo Y, and Xie H. Effects of epidermal growth factor on the follicle development and steroidogenesis of mouse fetal ovary in vitro. Journal of China Agricultural University. 2001, 6 (1): 1-6,
52. Wang H, Li M, Xia GL, Lu Z, Guo Y, and Zhang J. Effects of gonadotrophins on the mouse fetal ovarian follicle development and steroidogenesis in vitro. Chinese Journal of Veterinary Science. 2001, 21 (6): 617-621,
53. Guo Yong, Ni Hemin, Xia Guoliang, Zhu Yuding. Progress in cloning mammals from somatic cells, Progress in Biotechnology (China), 2000, (20): 44-49,
54. Yuding Zhu, Yong Guo, Hemin Ni. Progress in biotechnology of small ruminants in China, Small Ruminant Research, 1999, (34): 203-213,
55. Ni Hemin, Guo Yong, et al. Study on oocyte taken from live cows, Scientia Agricultura Sinica, 1999, (5): 87-95,
56. Guo Yong, Ni Hemin, et al. Improvement of microinjection system for transgenic rabbit embryos. Scientia Agricultura Sinica, 1998, (5): 69-74,
57. Guo Yong, Ni Hemin, et al. Progress on producing transgenic mammals by microinjection, Progress in Biotechnology(China), 1997, (1): 42-47,
58. Li J.F, Zhu YD, Yang WS, Guo Y, et al. Role of the introductory MAR for integration frequency in transgenic rabbits, High Technology Letters, 1996, (6): 1-3,
59. Yang WS, Ni HM, Guo Y. Study on Superovulation in female rabbits, Laboratory Animal Science and Administration, 1996, (13): 8-11,
60. Gao LY, Guo Yong, et al. Study on Effect of collecting embryo and histomorphological change of uterine mucosa in mice. Laboratory Animal Science and Administration, 1997, (14): 17-21,
倪和民，教授，1962年出生，1987年西北农林大科技学兽医专业毕业，1995获产科胚胎工程硕士学位；长期从事动物生殖生理和繁殖障碍方向的教学科研工作，主讲《动物产科学》及《动物行为学》两门兽医专业课程，及临床兽医专业研究生的《高级产科学》课程。任动物产科学会常务理事、养牛学会常务理事、及繁殖学会理事，担任农业部全国畜牧兽医总站胚胎生物技术专家、北京市奶牛科研创新团队岗位专家。
近五年主持课题如下：
1、2011.01-2013.12 国家自然基金 编号： 31072185
项目名称：不同来源植入前期绵羊胚胎IFN tau差异表达及其体外诱导子宫
上皮细胞Galectin15表达的研究；
2、2012.01-2016.12北京市奶牛科研创新团队岗位专家：奶牛疾病的防控
3、2012.01-2016.12 国家“863”计划项目:“牛羊分子细胞工程育种技术创新与优势性状新品种培育”的任务，子课题“黄淮肉用山羊分子细胞育种技术研究”。课题编号：2011AA100307，任务编号：2011AA100307-4。
4、2009.1-2012.06 国家“十一五转基因生物新品种·培育重大专项”课题
编号： 2009ZX08007-005B
项目名称：优质高效转基因肉牛新品种培育；
5、2011.01-2013.12 国家自然基金 编号： 31072185
项目名称：不同来源植入前期绵羊胚胎IFN tau差异表达及其体外诱导子宫
上皮细胞Galectin15表达的研究；
6、2009.01-2011.12 （横向）国家“十一五转基因生物新品种·培育重大专项”
课题编号： 008ZX08008-005-04 项目名称：抗关节炎脑炎转基因羊新品种培育研究
7、2011.01-2015.12 国家十二五计划863项目 编号： 2011AA10030
项目名称：黄淮山羊新品种的培育与开发利用
8、2008.1-2010.12 “863计划重点项目” 编号： 2008AA101003
项目名称：“家畜卵泡高效诱导发育技术研究与应用”一级子课题“绵羊有
腔卵泡卵母细胞成熟技术研究“；
9、2008.1-2010.12 国家“十一五支撑计划项目” 编号： 2008BADB2B04-4
项目名称： “优质肉用羊新品种选育与产业化开发”项目二级子课题“肉
羊高效育种关键技术的研究与应用” ；
10、2010.1-2010.12 国家自然基金面上项目 编号： 30972228
项目名称：“绵羊体外胚胎妊娠时MUC1, GLYCAM1和ISG15对子宫容受态影响
的研究”
11、2008.1-2009.12 北京市科委项目 编号： Z08050503260802
项目名称：北京少数民族乡村建设科技服务工程
12、2008.1-2009.12 农业部重点横向合作项目
项目名称：犬猫等宠物三聚氰胺和三聚氰酸重复剂量毒性和代谢动力研究
13、2008.1-2010.12 国家“十一五支撑计划项目” 编号： 2008BADB2B09-4
项目名称：优质种用肉牛肉羊扩繁技术研究
14、2007.7-2010.12 国家“十一五支撑计划项目” 编号： 2007BAD51B01-1-2项目名称：荣昌猪资源保护体系及关键技术研究
2012年7月，主持的转基因肉牛新品种培育项目，生出两头转入A-FABP基因的健康犊牛，实现了转基因技术育种的重大突破，标志着北京农学院具备了应用转基因技术，进行新品种培育的成熟技术体系。近五年来发表文章六十多篇，其中责任及第一作者文章30篇，30篇文章中一级核心期刊15篇，核心期刊文章12篇。
CURRICULUM VITAE
NAME: Ni，Hemin
GENDER: Male
DATE OF BIRTH: Dec 28, 1962
PLACE OF BIRTH: Shanxi , China
CITIZENSHIP: China
ADDRESS:
Office:
Department of Animal Science and Technology
Beijing University of Agriculture
Changping District, Huilongguan Beinong Road 7
Beijing , 102206
China
TELEPHONES:
Office: ( 8610) - 80793721
Fax: (8610) - 80799177
E-MAIL: nihemin@yahoo.com.cn
EDUCATION
|
Institution and Location
|
Degree
|
Year
Conferred
|
Filed of Study
|
|
Northwest Agricultural University
Northwest Agricultural and Forestall University
|
B.S.
M.S.
|
1987
1996
|
Veterinary Science
Veterinary Science
|
ACADEMIC APPOINTMENT
1987-1992: Lecturer in the Department of Animal Husbandry and Veterinary Science of Beijing Agricultural College.
1992-1997: Assistant Professor in the Department of Animal Husbandry and Veterinary Science of Beijing Agricultural College.
1999-2011: Associated Professor in the Department of Animal Science and Technology of Beijing Agricultural College.
2011.12- Professor in the College of Animal Science and Technology of Beijing University of Agriculture.
PROFESSIONAL AND RESEARCH EXPERIENCE
1985-1992: Focusing on teaching Poultry Science and Cattle Science in the Department of Animal Sciences in Beijing Agricultural College, and doing some research work on breeding of light layers, and on the application of some reproductive techniques (such as embryo transfer, embryo freezing, et al.) for sheep and dairy cattles.
1993-1997: Focusing on the nuclear transfer of bovine embryos, and production of transgenic rabbits and goats. Five transgenic rabbits (Human Insulin like Growth Factor-1, hIGF-1) and two transgenic goats (Bovine β-casein) were identified transgenic positively by Southern Blot Hybridization. Microinjection of foreign genes (such as bovine chamosin and hIGF-1) into bovine IVF (in vitro fertilization) embryos was also conducted. Construction of recombinant plasmids for gene transfer and positive transgenic animals were detected by PCR and Southern Blot Hybridization.
1998-2012 Focusing on the mechanism of ovine and bovine oocyte maturation in vitro by researching on the effects of EGF, PG and FSH AND LH on the development of their pre-implantation embryos. In vitro production of transgenic cloning of beef cattles.
Grant Support
National Fund for Natural Sciences of China ( 31072185, PI ) 2011/01/01 – 2013/12/31
The goal of this project is to explore the mechanism of the regulation of differential embryonic expression of IFNτ on different types of bovine embryos, and their in vitro induction of ISG15 on their uterine epithelium cells cultured in vitro. [ $5,600,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant (2009ZX08007-005B, PI ) 2009/01/01—2012/7/31
The goal of this project is to breed a new transgenic clonig beef cattle breed. [ $8,340,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant ( 2011ZX08008-005-03, PI ) 2011/08/01—2012/12/31
The goal of this project is to breed a new transgenic anti-arthritis encephalitis ovine breed. [ $8,340,0]
National Key Scientific and Technological Grant of China for Breeding New Transgenic Animals and Plants---Sub-grant ( 2008ZX08008-005-02, Co-investigator, PI: Liu Yun-hai )
The goal of this project is to breed a new transgenic anti-arthritis encephalitis ovine breed. [ $19,400,0]
2008/08/01
National Eleventh “5-year-plan” “863 High Tech Major Plan” of China---Sub-grant ( 2008AA1003， PI)
The goal of this project is to explore the mechanism of in vitro maturation for ovine oocytes . [ $4,500,0]
2009/01/01
PUBLICATIONS
1. Zhang Shaoyu, Liu Yunhai, Ni Hemin, Wang Hao, Gu Meichao, Yan Peng, Yang Fei,Guo Yong, Gene expression profile analysis of dormant mouse embryos preserved by controlled slow freezing, Acta Laboratorium Animals Scientia Sinica ,2012, 20(5): 15-19,
2. Chen Li-ping, Piao Xue-jiao, Luo Yong, Ni He-min, Liu Yun-hai, Guo Yong, Study on the in-vitro cultured methods for the uterine endometrical cells of dairy cattles and sheep, Chinese Agricultural Science Bulletin, 2012, 28(14): 99-104,
3. Li Kai#, Ni He-min#, Liu Yun-hai, Zhao Yan-wei, Qu Yang-yan, Li Xiao-yan, Guo Yong, LH plays a role to enhance the nuclear and cytoplasm synchronization for in vitro maturation of ovine oocytes, Scientia Agricultura Sinica,2011, 10（1）：136-141；(#：co-first author, *: correspondence author, indexed by SCIE)
4. Ni He-min*, Zhang Hong-bo, Liu Yun-hai, Deng Gui-xin, Lu Tian-gang, Guo Yong, The distribution of LH receptor on the ovaries among three different sheep breeds by different efficiency of superovulation, Acta Veterinaria et Zootechnica Sinica, 2011, 42(11): 1625-1631, (*: the first author and correspondence author)
5. Ni He-min*, Zhang Hong-bo, Liu Yun-hai, Lu Tian-gang, Deng Gui-xin, Guo Yong, Distribution of FSH receptor on the ovaries among different sheep breeds by different efficiency of superovulation, Scientia Agricultura Sinica,2011, 44（6）：1232-1238；
6. Tian Yu-jing, Lu Wen-geng, Zhang Yu, Lin Hao, Ni He-min, Guo Yong, Isolation and cultivation of bovine trophoblastic stem-like cell lines, Chinese Agricultural Science Bulletin, 2011, 27(26): 20-24,
7. Lin ZL, Gao Y, Deng GX, Liang HB, Zhang HB, Liu YH, Ni HM, Guo Y, Wang ZHG, Effect of estrus synchronization with PMSG and FSH on the distribution of estrogen receptor α in the mouse uterus, ovary and fallopian tube, Acta Laboratorium Animals Scientia Sinica ,2010, 18(3): 204-207,
8. Gao Y, Lin ZL, Zhang HB, Liang HB, Liu YH,Guo Y, Ni He-min*, Comparison of the expression of estrogen receptor α in mouse endometrium between those treated by estrus synchronization and in natural estrus, Acta Laboratorium Animals Scientia Sinica ,2010, 18(2): 168-171,
9. Liang HB, Liu JQ, Li FH, Xu HT, Niu JY, Li J, Sun Y, Guo Y, Liu YH, Comparison of different methods for boar sperm capacitation by CTC staining, China Animal Husbandry and Veterinary Medicine, 2010, 37(4): 171-173,
10. Liu YJ, Xia Y, Jin JN, Guo R, Liu YH, Guo Y, Li JH, Wei XL, Effect od different durations treated by luteinizing hormone on maturation in vitro of bovine oocytes, China Animal Husbandry and Veterinary Medicine, 2010, 37(5): 123-125,
11. Liu LQ, Guo Y, Liu YH, Xue JZH, Zhang H, Li XY, Ni HM, Effect of Calcium Ionophore and Caffeine on Ovine Sperm Capacitation in vitro, China Animal Husbandry and Veterinary Medicine, 2010, 37(1): 112-115,
12. Li K#, Ni HM#, Liu YH, Zhao YW, Qu YY, Li XY, Guo Y, LH plays a role to enhance the nuclear and cytoplasm synchronization for in vitro maturation of ovine oocytes, Scientia Agricultura Sinica,2009(10): 42(10):3633-3638, (*: correspondence author)
13. Li K, Mu YL, Han JL, Yang SL, Liu L, Yuan XX,Guo Y, Feng ST, Study on genetic variation of inbred families of Wuzhishan miniature pig using microsatellite DNA loci. Acta Veterinaria et Zootechnica Sinica, 2009, 40(3): 296-302,
14. Qin GS, Li HJ, Liang HB, Guo Y, Ni HM, Liu YH, In vitro production of early dairy cattle embryos by using X-bearing sperm. Chinese Journal of Animal Science, 2009,
15. Liu LQ, Liu YH, Guo Y, Yang FG, Ni HM, Comparison of the ovine sperm capacitation and fertilization in vitro among different concentration of serum collected from their different estrous stages. Acta Veterinaria et Zootechnica Sinica, 2009, 40(8): 1150-1156,
16. Qu YY, Liu YH, Guo Y, Li K, Zhao YW, Li XY, Ni He-min*, The tendency of mitochondrial distribution during maturation in vitro of ovine oocytes. Acta Veterinaria et Zootechnica Sinica, 2009, 40(8): 1258-1261,
17. Liu JW, Ni HM, Guo Y, Xu Y, Bao WY, Liu YH, Murine parthenogenetic embryonic development can be improved by the associated chemical activation. Chinese Journal of Zoology, 2009, 44(4): 135-141,
18. Li K, Feng ST, Mu YL, Yang SL,Han JL, Liu L, Yuan XX,Guo Y, Study on genetic regulation of microsatellite loci gene of three inbred families of Wuzhishan miniature pig. Scientia Agricultura Sinica, 2009, 42(5): 1751-1760,
19. Wu J, Ni HM, Liu YH, Guo Y, Bao WY, Xu Y, Wang XZ. Effect of different durations on nuclear maturation in vitro of feline oocytes. China Animal Husbandry and Veterinary Medicine, 2009, 36(3): 102-105,
20. Zhang HB, Qin GS, Liu YH, Guo Y, Li XY, Liu LQ, Ni He-min*Ni HM. Effect of estrogen and progesterone on the distribution of progesterone receptor on mouse endometrium of different pubescent ways. Acta Laboratorium Animals Scientia Sinica ,2009, 17(3): 206-209,
21. Bao WY, Liu YH, Guo Y, Xu Y, Wu J, Ni He-min*. Determination of the ovulation duration for domestic cats after superovulation during their non-breeding seasons. China Animal Husbandry and Veterinary Medicine, 2009, 35(10): 72-74
22. Liu LQ, Zhou WB, Gu S, Yang FG, Guo Y. Ovine Sperm Capacitation is not Affected by Their Reproductive Ducts during Different Reproductive Phases.Chinese Journal of Animal Science, 2008, 44(3): 13-15,
23. Zhang H, Liu YH, Ni HM, Yang FG, Liu LQ,Guo Y. Effect of Different Co-culture Cell Types on the Development of Ovine Parthenogenetic Embryos. Heilongjiang Animal Science and Veterinary Medicine, 2008, 316(5): 8-12,
24. Li XY, Ni HM, Liu YH, Zhao YW, Qu YY, Liu JW, Guo Y. Effect of PGE2 ,PGF2α and
Iloprost on Development in vitro of 2-cell Mouse Embryos. Acta Laboratorium Animals Scientia Sinica , 2008, 16(2): 122-126,
25. Bao WY, Liu YH, Guo Y, Xu Y, Wu J, Ni He-min*. Determination of the ovulation duration for domestic cats after superovulation during their Non-breeding seasons. China Animal Husbandry and Veterinary Medicine,2008, 35(10): 72-74,
26. Li K, Zhao YW, Guo Y, Liu YH, Lu TG, Qu YY, Ni He-min*, Effect of E2 and P4 on maturation in vitro of oocytes from Kunming mouse. Acta Laboratorium Animals Scientia Sinica , 2008, 16(4): 293-297,
27. Yang FG, Ni HM, Guo Y, Liu LQ, Zhang H, Liu YH. Effect of Butyrolactone on in vitro maturation and fertilization of Ovine Oocytes. Journal of Agricultural Biotechnology, 2008, 16(1): 66-70,
28. Liu LQ, Liu YH, Ni HM, Xue JZ, Zhang JT, Bai JL,Guo Y.Comparision of Ovine Sperm Capacitation in Different Animal Reproductive Ducts. Heilongjiang Animal Science and Veterinary Medicine, 2008, 312(1): 27-29,
29. Yang FG, Guo Y, Ni HM, Zhang H, Liu LQ, Xue JZ,Liu YH. Effect of Medium and Duration on In Vitro Maturation and Development of Ovine Parthenogenetic Embryos. Heilongjiang Animal Science and Veterinary Medicine, 2008, 312(1): 33-35,
30. ZHAO YW, LI K, Qu YY, LU TG, Liu YH, Guo Y, Ni He-min*. Effect of LH and hCG on
In Vitro Maturation of Oocytes from Kunming Mouse. Chinese Journal of Comparative Medicine, 2008, 18(2): 23-27,
31. Yang FG, Liu YH, Ni HM, Zhang H, Guo Y. Effect of Butyrolactone on Maturation in vitro and Developmental Competence of Ovine Oocytes. Chinese Journal of Animal Science, 2007, 43(23): 7-10,
33. Liu LQ, Liu CS, Guo Y, Ni HM, Zhang H, Yang FG, Liu YH. Comparison of CTC Staining and in Vitro Fertilization among Different Ovine Sperm Capacitation Methods. China Animal Husbandry and Veterinary Medicine, 2007,34(8): 31-34,
34. Zhang H, Liu YH, Ni HM, Yang FG, Liu LQ, Xue JZ, Guo Y. Effect of Media and Serum Concentration on Development of Ovine Parthenogenetic Embryos. China Animal Husbandry and Veterinary Medicine, 2007,34(7): 32-34,
35. Xue JZ, Liu YH, Guo Y, Liu LQ, Zhang H, Yang FG, Ni He-min*. Effect of Different Concentrations of Progesterone on Ovine Sperm Capacitation in vitro, Journal of Guangxi Agric and Biol Science, 2006, 25(supp): 63-66,
36. rnal of China Agricultural University. 2001, 6 (1): 1-6,
37. Guo Yong, Ni Hemin, Xia Guoliang, Zhu Yuding. Progress in cloning mammals from somatic cells, Progress in Biotechnology (China), 2000, (20): 44-49,
38. Yuding Zhu, Yong Guo, Ni He-min*. Progress in biotechnology of small ruminants in China, Small Ruminant Research, 1999, (34): 203-213,
39. Ni He-min*, Guo Yong, et al. Study on oocyte taken from live cows, Scientia Agricultura Sinica, 1999, (5): 87-95,
40. Guo Yong, Ni Hemin, et al. Improvement of microinjection system for transgenic rabbit embryos. Scientia Agricultura Sinica, 1998, (5): 69-74,
41. Guo Yong, Ni Hemin, et al. Progress on producing transgenic mammals by microinjection, Progress in Biotechnology(China), 1997, (1): 42-47,
Yang WS, Ni HM, Guo Y. Study on Superovulation in female rabbits, Laboratory Animal Science and Administration, 1996, (13): 8-11,
高建明，女,1960年12月出生，中共党员。 1983年毕业于北京农学院畜牧专业，获农学学士学位，1996年获中国农业科学院动物繁殖专业硕士学位。1983年北京农学院留校任教。 1983—1988年任助教，1988—1997年任讲师，1997—2002年任副教授，2002年至今为北京农学院动物科学技术学院教授，基础兽医学、临床兽医学硕士生导师及养殖领域（专业学位）导师。研究方向：动物繁殖生物技术，主要从事哺乳动物卵巢、配子和胚胎生长发育机理的研究，并首次提出进行中药有效成分对胚胎体外发育的作用研究。社会兼职：中国畜牧兽医学会动物繁殖学分会常务理事，北京畜牧兽医学会理事会理事，《中国农业科学》、《畜牧兽医学报》、《中国畜牧杂志》等期刊审稿专家。曾被评为北京市高等学校优秀青年骨干教师、入选北京市跨世纪优秀人才、北京农学院学科带头人、北京农学院教书育人先进工作者。2011年在教育部、科学技术部、中国科学院、国家自然科学基金委员会联合开展的“10000个科学难题”征集活动中荣获“优秀撰稿人”奖荣誉证书。2010年被《中国农业科学》评为优秀审稿专家。2011年获北京农学院研究生就业工作突出贡献导师。
教学工作
承担《动物繁殖学》、《动物胚胎工程》、《哺乳动物性别控制》、《科学研究的方法》等本科生课程；承担《高级组织胚胎学》、《动物繁殖理论与生物技术》、《实验设计与科技写作》等研究生课程。
2006、2008、2012年 分别在中国畜牧兽医学会动物繁殖学分会学术研讨会上获得“优秀论文”奖；指导的多名研究生考入中国农业大学和北京大学攻读博士，且多名研究生被评为北京农学院优秀毕业生。
科研工作
作为骨干主体人员参加完成了国家自然科学基金项目、国家“七五”科技攻关项目子课题、市科委重点课题等4项。主持完成了北京市教委、北京市自然科学基金、北京市优秀人才、开放课题等多项课题。现主持北京市自然科学基金项目“中药单体成分调控小鼠附植前胚胎抗凋亡基因miRNA-21的研究” (No.6112004)、北京农学院高质量论文项目“DNA甲基转移酶3a在小鼠卵泡膜细胞分化过程中作用机制” (No.Gl2012006)、参加北京市属高校人才强教深化计划“学术创新团队建设计划”主持有关“热应激对动物繁殖和胚胎发育的影响研究”和主持1项国家“十二五”科技支撑计划项目子课题(No.2011BAD34B01-07)。获一项国家科技进步三等奖，两项市科技进步二等奖，一项北京市发明展览会金牌奖。主编出版教材2部，参编出版教材6部；主编出版著作3部。以第一作者或通讯作者发表研究论文80余篇。
Gao Jianming, female, born in December 1960, member of the Communist Party of China, graduated from the animal husbandry major of Beijing University of Agriculture and got bachelor of agriculture degree in 1983, got master of animal reproduction of the Chinese Academy of Agricultural Sciences in 1996.Teaches in Beijing University of Agriculture from 1983. Worked as teaching assistant, lecturer and associate professor separately during 1983-1988, 1988-1997 and 1997-2002. Professor of animal science and technology college of Beijing University of Agriculture since 2002, tutor for graduate of basic veterinary medicine, clinical veterinary medicine and breeding field (professional degree). Research area: animal reproductive biotechnology.The main research is about the mechanism of mammalian ovary, gamete and embryo development. And researched the effect of Chinese traditional medicine effective components on embryo development in vitro as the first in domestic and foreign. Social Appointments: executive director of Animal Reproductive Committee of Chinese Association of Animal Science and Veterinary Medicine, director of Beijing Association of Animal Science and Veterinary Medicine. Reviewer of Scintia Agricultura Sinica, Acta Veterinaria et Zootechnica Sinica, Chinese Journal of Animal Science, etc. Rated as the key member of the outstanding young teacher of institution of higher education in Beijing and selected as the cross-century talents of Beijing, the academic leader of Beijing University of Agriculture and the advanced worker in imparting knowledge and educating people of Beijing University of Agriculture. Awarded Excellent Copywriter Honor certificate by the Collection Activity of 10000 scientific problems, which was jointly hosted in 2011 by Ministry of Education, Ministry of Science and Technology, Chinese Academy of Sciences and Committee of National Natural Science Foundation of China. Rated as the excellent reviewer by Scintia Agricultura Sinica in 2010 and the Mentor of Beijing University of Agriculture who make prominent contribution to the problem of graduate students finding jobs in 2011.
Teaching Profession
Undertakes some undergraduate courses such as Animal Reproduction, Animal Embryonic Engineering, Mammalian Sex Control, Method of Scientific Research and some graduate courses such as Advanced Animal Histology and Embryology, Animal reproduction theory and biotechnology, Experimental Design and scientific paper writing and so on.
Instructed postgraduates to win the prizes of distinguished paper in the academic conferences that were held by Animal Reproductive Committee of Chinese Association of Animal Science and Veterinary Medicine in 2006, 2008 and 2012. Meanwhile, some postgraduates were admitted to Dr. of China Agricultural University and Peking University and some were rated as the excellent postgraduate of Beijing University of Agriculture.
Scientific Research
As one of main backbone members, participated and contributed to the achievement of 4 major research projects such as National Natural Science Foundation of China, National scientific and technological project and the key research projects of Beijing Science and Technology Commission. As a director, many research projects that were funded by Beijing Education Commission, Beijing Natural Science Foundation and Open Projects were completed. For now, taking charge of one Beijing Natural Science Foundation named "Research on the effectiveness of Chinese traditional medicine monomer in regulating anti-apoptosis gene miRNA-21" (No.6112004), and one High Quality Paper project of Beijing University of Agriculture named "Efeect and mechanism of Dnmt3a during follicular thecal cells differentiation in mice" (No.Gl2012006). Participating the "Academic Innovation Team Ponstructing Project" which is the Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality and in charge of the part about "Effect of heat-stress on animal reproduction and embryo development". In charge of a sub subject of National Twelve-Five Technological Supported Plan of China (No.2011BAD34B01-07). By now, won one third prize of National Scientific and Technological Progress, one second prize of Beijing Scientific and Technological Progress, one second prize of Shanghai Scientific and Technological Progress and one Beijing Invention Exhibition gold medal. Edited and published two teaching materials as an editor in chief and participated in editing and publishing six teaching materials. Edited and published three works as an editor in chief. Published more than 80 papers as first author or corresponding author.
宠物临床方向
张中文，男、副教授、硕士，日本麻布大学留学归国人员。现任全国小动物分会理事。主要研究方向：宠物临床（肾病与眼科疾病）。主持“十一.五”科技支撑计划子课题1项（中兽药药效评价模型及其关键技术研究-肠速康临床药效学试验研究子课题任务书编号：2008BADB4B01-8），北京市教委科技项目2项（中西医结合防治奶牛流产的研究，KM 20051005002等）；参加国家自然科学基金项目2项，在英国、德国、中国等发表科技论文50余篇，其中4篇被SCI收录，主编出版著作、教材6部，申报国家发明专利3项。获得省部级科技奖1项，北京市教育教学成果二等奖1项。
代表性论著：
［1］ TGF-beta1/Smads signaling stimulates renal interstitial fibrosis in experimental AAN. Journal of Receptors and Signal Transduction,29（5）：280-285，2009（并列第一作者,SCI收录）
［2］ 小鼠肾小管上皮细胞的原代培养及鉴定［J］．解剖学报，2007，12(6)：765-767(通讯作者)
［3］ 三聚氰胺对小鼠肾脏的影响及中药治疗试验.动物医学进展,2008,29(12):31-33(通讯作者)
任晓明教授简历
任晓明，男，1958年6月出生于吉林省双辽市，汉族，留学归国博士。现任北京农学院动物科学技术学院动物医学系主任，教授。兼任中国实验动物学会农业实验动物专业委员会副主任；中国畜牧兽医学会信息技术分会理事；中国畜牧业协会猪业分会理事、禽业分会理事，九三学社北京市农林委员会委员等职。
1982年毕业于延边大学农学院兽医系兽医专业，获得了学士学位；1985年毕业于中国农业大学动物医学院，获得了硕士学位。在1989~1997年间，作为国家派出的访问学者和留学生，在日本度过了八年的留学生活。先后在日本大学、北海道大学、麻布大学、日本实验动物中央研究所等单位工作、留学，获得了日本兽医学博士学位。
留学前在中国农业大学动物医学院任教，从事我国当时的新兴学科—《实验动物学》的教学和科研工作，建立了我国实验动物学的分枝学科—《实验动物技术》，主编了全国高等学校统编教材《实验动物技术》。留学归国后，曾任中国医学科学院实验动物研究所所长助理，北京协和医科大学实验动物学部主任助理，中国实验动物学会野生动物分会主任委员，中美合资北京九州大地集团技术总监，中美合资北京资源集团饲料种猪事业部总裁，北京实验动物学会常务理事，北京饲料协会常务理事等职。2004年作为高层次人才引进了北京农学院。
主编了《实验动物技术》，《猪病学》，《猪在生物医学研究中的应用》，《实验动物育种学》，《兽医基础》，《动物常见病防治》，《新鱼病图谱》、《小动物软组织外科技术》，《新鱼病图谱》，《猪病快速临床诊断法指南》，《新养猪法》,《怎样养鲇鱼》，《怎样养鲈鱼》，《怎样养泥鳅》等10多部教材、专著。在国内外学术期刊上发表了40多篇论文。
曾获得农业部科技进步二等奖；北京市高等教育教学成果二等奖；北京农学院教育教学成果一等奖等奖项。
Ren Xiaoming, male, Han nationality, returned oversea doctor, born in Shuangliao, Jilin Province in June, 1958, am the executive and professor of Veterinary Medicine Department, Animal Science College, Beijing University of Agriculture, and concurrently the vice-executive of Agricultural Laboratory Animal Professional Committee, China Laboratory Animal Science Association, the councilor of Pig Husbandry Chapter and Poultry Husbandry Chapter of China Animal Husbandry Association, the commissioner of Beijing Agriculture and Forestry Committee, Jiusan Society, etc.
Obtained bachelor degree in 1982 from Veterinary Medicine Department, Agricultural College, Yanbian University; obtained the master degree in 1985 from Veterinary Medicine College, China Agricultural University. Studied in Japan from 1989 to 1997 as the visiting scholar and oversea student. Successively learned and worked in Japan University, Hokkaido University, Azabu University, Japan Laboratory Animal Centre Institute, and obtained the doctor’s degree.
Before the oversea studying period, had engaged in teaching and researching in the burgeoning field, “laboratory animal”, and established the branch of the china laboratory animal subject, “Laboratory Animal Techniques”, and edit the teaching material “Laboratory Animal Techniques” which is the state-compiled textbook of higher learning.
Used to be the former director assistance of Laboratory Animal Institute of China Medicine Academy of Science, the former executive assistance of Laboratory Animal Department of Peking Union Medical College, the former councilor of Wild Animal Branch Committee of China Laboratory Animal Committee, the former director of technology of Sino-US joint venture, Peking Jiuzhoudadi Corporation Group, the former chief executive officer of Feed and Breeding Pig Department of Sino-US joint venture, Peking Resource Corporation Group, the former general councilor of Beijing Laboratory Animal Society, the former general councilor of Beijing Feed Society before taking office in Beijing University of Agriculture as the high level talents in 2004.
Used to edit more than 10 textbooks and monographs as the chief editor including “Laboratory Animal Technique”, “Hyoiatrics”, “Pigs’ Application In Biomedical Research”, “Laboratory Animal Breeding Science”, “Basic Veterinary Medicine”, “Prevention & Cure Against Common Animal Diseases”, “New Atlas Of Fish Diseases”, “Small Animal Soft Tissue Surgery Techniques”, “Quick Clinical Diagnosis Guides For Pig Diseases”, “New Methods to Raise Pigs”, “How To Raise Catfish”, “How To Raise Loach”. And published more than 40 papers in academic journal at home and abroad.
Won the second class of “Science And Technology Progress Prize” presented by Ministry Of Agriculture, the second class of “Beijing Higher Education Teaching Achievement Prize” and the first class of “Education And Teaching Achievement Prize”of Beijing University Of Agriculture
.
菅沼常德，男（1946年～）教授，博士，兽医师，日本麻布大学兽医学部研究生院博士研究生导师。1969年麻布兽医科大学兽医学部毕业，1971年硕士研究生毕业，1974年博士研究生毕业，1981-1982年留学美国华盛顿州立大学，历任麻布大学讲师、副教授，教授。现兼任麻布大学国际交流委员会委员长，日本兽医影像学会兽医影像杂志编委会委员长等职务。
教学方面主讲《兽医影像学》、《兽医影像实习》、《兽医学特论》、《兽医放射线学特论》等必修课程，共同承担《小动物兽医综合临床》、《产业动物兽医综合临床》及实习等必修课程。
长期从事兽医影响临床实验与科研工作，精通动物X线、 超声、CT和核磁共振等影像诊断技术。目前主要主持综合影像诊断法相关的临床研究X线、超声波、内窥镜、T和核磁共振等综合诊断法的有效性研究；恶性肿瘤的放射线疗法研究—最佳放疗条件研究；动物椎间盘病新激光照射微创疗法研究；高压疗法动物疾病治疗的有效性研究等科研项目，指导博士研究生多人，发表学术论文多篇、专译著多部。
姚华，女，汉族，博士。2006年7月毕业于中国农业大学临床兽医学专业，获农学博士学位；2006年-2008年在军事医学科学院基础医学博士后流动站进行研究工作。2008年到北京农学院主要从事兽医临床肿瘤疾病和营养代谢病的诊疗与机制研究。社会兼职：中国畜牧兽医学会小动物医学分会会员，华北地区家畜内科学分会常务理事，中国体视学学会会员，中国畜牧兽医学会家畜内科学分会会员。
教学方面：讲授《动物内科学》、《动物营养代谢病学》、研究生课程《临床兽医学进展》，获北京农学院2011年青年教师基本功比赛一等奖，获第七届北京市青年教师基本功比赛理工类B组二等奖。
科研方面：主持课题有北京市科技新星项目1项，北京农学院三项基金重点项目1项，北京市教委项目1项，北京农学院科研提高项目1项，企业横向课题1项。同时参与国家自然科学基金项目、北京市自然科学基金项目及科技部攻关项目子课题的研究。
Hua Yao is working at Beijing University of Agriculture in the College of Animal Science and Veterinary Medicine. She received her Ph.D. in Clinical Veterinary Medicine from China Agricultural University and immediately began research on pathology. Two years later, Hua returned to Beijing University of Agriculture to work in Internal Veterinary Medicine with a special emphasis on diagnosis and treatment of small animal disease and metabolic disease in animals. She is currently a lecturer for undergraduate students in diagnosing and treating patients, and for graduate students in the development of clinical veterinary medicine. Her research focuses on the mechanism of canine mammary tumor. She also has had the opportunity to teach in the Animal Teaching Hospital at Beijing University. Her future goals include studying the best method for pathologic diagnoses using animal tumor cases as well as the classification of tumors.
